Applications

Dr. Atom Sarkar, now a neurosurgeon at Ohio State University Medical Centre (Columbus, Ohio), in collaboration with Prof Julio Ferdandez from Columbia University (New York, NY), has been interested in the role of...

The entire development of the nervous system can now be viewed with excellent temporal resolution using the exceptional capture rate of the Neo sCMOS combined with the Light Sheet Microscopy technique...

Spatial light interference microscopy (SLIM) is a highly sensitive quantitative phase imaging method, which is capable of unprecedented structure studies in biology and beyond. SLIM combines two classical ideas in optics and...

In the past few years we have witnessed an unprecedented evolution of imaging techniques, directed at helping researchers break through what was previously regarded as an immutable optical resolution limit...

Lampe et al have developed a novel variant of direct STORM (dSTORM) termed spectral demixing dSTORM (SD-dSTORM) that combines the photochemical advantages of the red emitting carbocyanine dyes with the principal...

The researchers transfected Neuro-2A cells with a single fusion construct of pHRed-Perceval targeted to the plasma membrane and the nucleus. The Andor Revolution DSD was used to collect both widefield and confocal signals...

Light microscopy has always been suffering from the limit imposed by the Abbe′s law which manifested itself as presence of Airy disks. These structures defined the resolution of any optical systems regardless of imaging...

When the aim of an experiment is to image single molecules, autofluorescence background can impede their detection. In cells, a major contribution to the fluorescence background is from autofluorescence from within the cell...

Recently, Nissim-Rafinia and Meshorer (ref. 1), from the department of genetics in the Alexander Silberman Institute of Life Sciences at the Hebrew University of Jerusalem, used active illumination and the technique known...