Applications

Protein Unfolding
Protein Unfolding

Dr. Atom Sarkar, now a neurosurgeon at Ohio State University Medical Centre (Columbus, Ohio), in collaboration with Prof Julio Ferdandez from Columbia University (New York, NY), has been interested in the role of...


March 16, 2016
Light Sheet Microscopy
Light Sheet Microscopy

The entire development of the nervous system can now be viewed with excellent temporal resolution using the exceptional capture rate of the Neo sCMOS combined with the Light Sheet Microscopy technique...


March 16, 2016
Spatial Light Interference Microscopy (SLIM)
Spatial Light Interference Microscopy (SLIM)

Spatial light interference microscopy (SLIM) is a highly sensitive quantitative phase imaging method, which is capable of unprecedented structure studies in biology and beyond. SLIM combines two classical ideas in optics and...


March 16, 2016
Double-Helix and Super-Resolution an Unlikely Connection
Double-Helix and Super-Resolution an Unlikely Connection

In the past few years we have witnessed an unprecedented evolution of imaging techniques, directed at helping researchers break through what was previously regarded as an immutable optical resolution limit...


March 16, 2016
Multi-color Direct STORM
Multi-color Direct STORM

Lampe et al have developed a novel variant of direct STORM (dSTORM) termed spectral demixing dSTORM (SD-dSTORM) that combines the photochemical advantages of the red emitting carbocyanine dyes with the principal...


March 16, 2016
Imaging Intracellular pH in Living Cells
Imaging Intracellular pH in Living Cells

The researchers transfected Neuro-2A cells with a single fusion construct of pHRed-Perceval targeted to the plasma membrane and the nucleus. The Andor Revolution DSD was used to collect both widefield and confocal signals...


March 16, 2016
PALMIRA Novel Nanoscopy Technique
PALMIRA Novel Nanoscopy Technique

Light microscopy has always been suffering from the limit imposed by the Abbe′s law which manifested itself as presence of Airy disks. These structures defined the resolution of any optical systems regardless of imaging...


March 16, 2016
NIR Dyes to Deal With Autofluore-scence in Biological Samples
NIR Dyes to Deal With Autofluore-scence in Biological Samples

When the aim of an experiment is to image single molecules, autofluorescence background can impede their detection. In cells, a major contribution to the fluorescence background is from autofluorescence from within the cell...


March 16, 2016
Study of Dynamics of Chromatin Binding Proteins
Study of Dynamics of Chromatin Binding Proteins

Recently, Nissim-Rafinia and Meshorer (ref. 1), from the department of genetics in the Alexander Silberman Institute of Life Sciences at the Hebrew University of Jerusalem, used active illumination and the technique known...


March 16, 2016

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